Tavassoli F A
Am J Surg Pathol. 1983 Jan;7(1):73-84. doi: 10.1097/00000478-198301000-00008.
This report describes a previously unreported type of ovarian tumor containing three distinct components: germ cells, gonadal stromal cells, and epithelial cells. The germ cells were mainly of the types seen in various stages of oogenesis. The gonadal stromal component had two lines of differentiation. Cells containing Charcot-Böttcher filaments were identified as Sertoli cells and granulosa cells were characterized by a microfollicular arrangement. The epithelial component resembled the cells present on the ovarian surface and lacked specific differentiation toward any of the common ovarian (müllerian) epithelial cell lines. The tumor was discovered as an abdominal mass in a newborn girl with a 46XX karyotype. Subsequently, the child has developed normally and is well 7 years after surgery.
本报告描述了一种此前未报告过的卵巢肿瘤，其包含三种不同成分：生殖细胞、性腺间质细胞和上皮细胞。生殖细胞主要为在卵子发生各个阶段所见的类型。性腺间质成分有两条分化途径。含有夏科 - 博歇细丝的细胞被鉴定为支持细胞，颗粒细胞的特征为微滤泡排列。上皮成分类似于卵巢表面的细胞，且未向任何常见的卵巢（苗勒氏）上皮细胞系发生特异性分化。该肿瘤是在一名核型为46XX的新生女婴中作为腹部肿块被发现的。随后，该患儿发育正常，术后7年情况良好。
