Cohen S
Cancer. 1983 May 15;51(10):1787-91. doi: 10.1002/1097-0142(19830515)51:10<1787::aid-cncr2820511004>3.0.co;2-a.
This review summarizes briefly some of the historical aspects of the discovery, isolation, and mode of action of epidermal growth factor (EGF). Also considered are some of the key experiments which relate the biochemical mechanisms of EGF action to the mechanism involved in oncogenic transformation by the retroviruses.
本综述简要总结了表皮生长因子(EGF)发现、分离及其作用方式的一些历史方面。还考虑了一些关键实验,这些实验将EGF作用的生化机制与逆转录病毒致癌转化所涉及的机制联系起来。