纤维组织细胞瘤细胞系：小鼠和人类的染色体研究

Fibrous histiocytoma cell line: chromosome studies of mouse and man.

作者信息

Hecht F, Berger C, Hecht B K, Speiser B L

出版信息

Cancer Genet Cytogenet. 1983 Apr;8(4):359-62. doi: 10.1016/0165-4608(83)90076-6.

Abstract

A human cell line isolated from a lung metastasis of a malignant fibrous histiocytoma was studied chromosomally. The cell line had a modal chromosome number of 59 with multiple numerical and morphologic chromosome changes and marker chromosomes. A putative clone from this cell line had a modal number of 41 with exclusively acrocentric chromosomes and was clearly not human but mouse in origin.

摘要

对从恶性纤维组织细胞瘤肺转移灶分离出的人细胞系进行了染色体研究。该细胞系的众数染色体数为59，伴有多种数量和形态上的染色体改变以及标记染色体。该细胞系的一个假定克隆的众数为41，只有近端着丝粒染色体，显然并非源自人类，而是源自小鼠。