Phares C K, Nguyen Duy A i
J Helminthol. 1982 Dec;56(4):315-22. doi: 10.1017/s0022149x00034702.
The effects of infection with plerocercoids of Spirometra mansonoides on tissue glycogen deposition of rats was determined. Hypophysectomized rats infected for two days had higher liver glycogen concentrations than controls and this effect was greatest after one week. Elevated liver glycogen associated with plerocercoid infection was observed in fed animals both at the beginning and at the end of the light period as well as after an overnight fast. Glycogen phosphorylase (1,4 alpha D glucan: orthophosphate alpha glucosyltransferase EC 2.4.1.1.) was inhibited but glucose-6-phosphatase (EC 3.1.3.9) was unaffected in the livers of infected hypophysectomized rats. While this effect is similar to actions of both growth hormone and insulin, plerocercoid infection had no influence on glycogen of cardiac or skeletal muscle at any time. Plerocercoid infection had no effect on the glycogen concentration of any tissue of intact rats.
测定曼氏迭宫绦虫裂头蚴感染对大鼠组织糖原沉积的影响。感染两天的垂体切除大鼠肝脏糖原浓度高于对照组，且这种效应在一周后最为明显。在光照期开始和结束时以及禁食一夜后，喂食的动物中均观察到与裂头蚴感染相关的肝脏糖原升高。糖原磷酸化酶（1,4-α-D-葡聚糖：正磷酸α-葡糖基转移酶，EC 2.4.1.1.）受到抑制，但感染的垂体切除大鼠肝脏中的葡萄糖-6-磷酸酶（EC 3.1.3.9）未受影响。虽然这种效应类似于生长激素和胰岛素的作用，但裂头蚴感染在任何时候对心肌或骨骼肌的糖原均无影响。裂头蚴感染对完整大鼠任何组织的糖原浓度均无影响。
