Studies on polyphosphoinositides in developing rat brain.

Polyphosphoinositides in rat brain exist in two forms: the metabolically active form that is readily attacked by the polyphosphoinositide phosphohydrolases, and the inert form that is attacked by the enzymes at a slower rate. The two pools continue to increase even during the postweaning period, suggesting a role in glial as well as myelin development apart from their role in neurons.