对兔眼给药后Δ9-四氢大麻酚的全身吸收。
Systemic absorption of delta 9-tetrahydrocannabinol after ophthalmic administration to the rabbit.
作者信息
Chiang C W, Barnett G, Brine D
出版信息
J Pharm Sci. 1983 Feb;72(2):136-8. doi: 10.1002/jps.2600720210.
PMID:6300368
Abstract
delta 9-Tetrahydrocannabinol was given by ophthalmic administration to the rabbit. Plasma concentrations were measured for two strengths of ophthalmic solution and compared with intravenous data to establish bioavailability. Absorption was variable, while maximum plasma levels were sustained for several hours.
摘要
将9-四氢大麻酚通过眼部给药给予兔子。测量了两种浓度的眼用溶液的血浆浓度，并与静脉注射数据进行比较以确定生物利用度。吸收情况不稳定，而血浆最高水平可持续数小时。
Zotero 插件