内源性阿片类物质：1981年。

Endogenous opiates: 1981.

作者信息

Olson G A, Olson R D, Kastin A J, Coy D H

出版信息

Peptides. 1982 Nov-Dec;3(6):1039-72. doi: 10.1016/0196-9781(82)90075-4.

Abstract

This paper is the fourth of an annual series reviewing the research concerning the endogenous opiate peptides. This installment covers only work published during 1981 and attempts to provide a comprehensive, but not exhaustive, survey of the area. Previous papers in the series have dealt with research done before 1981. Topics concerning endogenous opiates reviewed here include a delineation of their receptors, their distribution, their precursors and degradation, behavioral effects resulting from their administration, their possible involvement in physiological responses, and their interactions with other peptides and hormones. Due to the burgeoning literature in this field, the comprehensive nature of this review in the future will be limited to considerations of behavioral phenomena related to the endogenous opiates.

摘要

本文是关于内源性阿片肽研究年度系列综述的第四篇。本期仅涵盖1981年发表的研究，并试图对该领域进行全面但非详尽无遗的调查。该系列的前几篇论文涉及1981年以前的研究。这里综述的关于内源性阿片肽的主题包括其受体的描述、分布、前体和降解、给药后的行为效应、它们可能参与的生理反应以及它们与其他肽和激素的相互作用。由于该领域文献的迅速增加，未来这篇综述的全面性将仅限于与内源性阿片肽相关的行为现象的考量。