[Effect of regeneration of hematopoietic organs on the number and type of splenic colonies].

Two thirds of the spleen or the bone marrow of the tibia were removed in CBA mice. Hemopoietic splenic colonies were obtained and examined microscopically on the 8th day after the lethal irradiation of mice and injection of the spleen cell suspension. An increase of the number of colonies and a significant rise of the number of granulocytopoietic colonices in comparison with their number in control was seen in the experimental animals. The number of other hemopoietic colonies remained unchanged. The authors suggest that these changes could be caused by the local influence of the proliferating spleen stroma, or by a factor secreted from the regenerating stroma of the hemopoietic organs.