Sukhova G K, Podrabinek T R, Kharlova G V
Biull Eksp Biol Med. 1978 Feb;85(2):219-21.
Two thirds of the spleen or the bone marrow of the tibia were removed in CBA mice. Hemopoietic splenic colonies were obtained and examined microscopically on the 8th day after the lethal irradiation of mice and injection of the spleen cell suspension. An increase of the number of colonies and a significant rise of the number of granulocytopoietic colonices in comparison with their number in control was seen in the experimental animals. The number of other hemopoietic colonies remained unchanged. The authors suggest that these changes could be caused by the local influence of the proliferating spleen stroma, or by a factor secreted from the regenerating stroma of the hemopoietic organs.
切除CBA小鼠三分之二的脾脏或胫骨骨髓。在对小鼠进行致死性照射并注射脾细胞悬液后的第8天，获取造血脾集落并进行显微镜检查。与对照组相比，实验动物的集落数量增加，粒细胞生成集落的数量显著上升。其他造血集落的数量保持不变。作者认为，这些变化可能是由增殖的脾基质的局部影响，或造血器官再生基质分泌的一种因子引起的。
