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[一例无白蛋白血症病例的生物学研究]

[Biological study of a case of analbuminemia].

作者信息

Reynaud J P, Sagniez M, Rousseau A, Nicolas G

出版信息

Sem Hop. 1983 Jan 13;59(2):124-8.

PMID:6301031
Abstract

A new case of analbuminemia in a fifty-four-year-old French woman is described. The patient was admitted to a hospital cardiology department for thoracic pain. Consanguinity between the patient's parents was established. Proteins were studied both during the acute phase and the subsequent remission. Total serum protein concentrations were stable, around 5.3 g. Hypoalbuminemia was compensated initially by alpha-2-globulins and subsequently by beta globulins. Increases in serum cholesterol and serum beta lipoproteins were recorded. Hydroelectrolytic balance was normal. Orthostatic renin and aldosterone release was significantly increased, denoting response to lowered hydrostatic pressure. A minor increase in serum thyroxin was recorded, probably because of the increase in thyroxin binding globulin.

摘要

本文描述了一名54岁法国女性患无白蛋白血症的新病例。该患者因胸痛入住医院心脏病科。确定患者父母为近亲。在急性期和随后的缓解期均对蛋白质进行了研究。血清总蛋白浓度稳定,约为5.3克。低白蛋白血症最初由α-2球蛋白代偿,随后由β球蛋白代偿。记录到血清胆固醇和血清β脂蛋白升高。水电解质平衡正常。直立位肾素和醛固酮释放显著增加,表明对静水压降低有反应。记录到血清甲状腺素略有升高,可能是由于甲状腺素结合球蛋白增加所致。

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