Grundmann R, Schwarzkopf N, Oette K
Infusionsther Klin Ernahr. 1985 Oct;12(5):246-50.
The effects of 20 and 40 g postoperative intravenous human albumin (HA) infusion on the serum protein fractions and on the colloid osmotic pressure (COP) were analyzed in 72 septic and aseptic patients. Only aseptic patients showed an increase in the COP as well as the serum albumin concentration during at least a 24-h-period. In septic patients, however, the increased serum albumin concentration dropped rapidly to the initial values. This can be only explained by a disturbance of the membrane permeability. In contrast, the behavior of the serum globulin concentration was not essentially influenced by septic or non septic conditions.
分析了72例脓毒症和非脓毒症患者术后静脉输注20克和40克人血白蛋白（HA）对血清蛋白组分和胶体渗透压（COP）的影响。只有非脓毒症患者在至少24小时内COP以及血清白蛋白浓度有所升高。然而，在脓毒症患者中，升高的血清白蛋白浓度迅速降至初始值。这只能用膜通透性紊乱来解释。相比之下，血清球蛋白浓度的变化基本上不受脓毒症或非脓毒症状态的影响。
