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[超氧化物歧化酶治疗2例放射性硬化症]

[Superoxide dismutase treatment of 2 cases of radiation-induced sclerosis].

作者信息

Emerit J, Michelson A M, Robert H G, Chomette G, Guérin R A, Blondon J, Bertrand M

出版信息

Sem Hop. 1983 Jan 27;59(4):277-81.

PMID:6301059
Abstract

Two patients with severe radio-induced necrosis were treated with bovine copper superoxide dismutase encapsulated in lysosomes (SOD). Two milligrams were injected subcutaneously every other day. This therapy was apparently effective on radio-induced inflammation and fibrosis. These are preliminary results that need confirmation. They suggest that SOD is useful, not only before radiation exposure, as a preventive, but also after exposure, as curative treatment for radiation injury.

摘要

两名患有严重放射性坏死的患者接受了包裹在溶酶体中的牛铜超氧化物歧化酶(SOD)治疗。每隔一天皮下注射2毫克。这种疗法对放射性炎症和纤维化显然有效。这些是需要确认的初步结果。它们表明,SOD不仅在辐射暴露前作为预防措施有用,而且在暴露后作为辐射损伤的治疗方法也有用。

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