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[小细胞支气管癌的联合治疗]

[Combination treatment of small cell bronchial carcinoma].

作者信息

Voss A C, Steinke B, Ostendorf P, Teller P, Gnann H

出版信息

Strahlentherapie. 1983 Jan;159(1):18-21.

PMID:6301108
Abstract

35 cases with micro-cellular bronchial carcinoma are described. The patients are treated with a combination of a modified ACO scheme and fractionated irradiations with 50 to 60 Gy to the primary tumor and 30 Gy to the encephalic skull. Among 14 patients with local disease, ten had a complete remission and three a partial remission. Among 21 patients with advanced disease, six had a complete remission and eight a partial remission. The side effects were not important, and they were not reinforced by the higher dose of the primary irradiation. The local recurrence rate was decreased, but the average survival times were not prolonged, because these are still dependent upon the hematogenic formation of metastases.

摘要

本文描述了35例微细胞支气管癌患者。患者接受改良ACO方案联合分次放疗,原发肿瘤剂量为50至60 Gy,脑颅骨剂量为30 Gy。在14例局部病变患者中,10例完全缓解,3例部分缓解。在21例晚期病变患者中,6例完全缓解,8例部分缓解。副作用并不严重,且较高剂量的原发照射并未加重副作用。局部复发率降低,但平均生存时间并未延长,因为这仍取决于转移灶的血行形成。

相似文献

1
[Combination treatment of small cell bronchial carcinoma].[小细胞支气管癌的联合治疗]
Strahlentherapie. 1983 Jan;159(1):18-21.
2
[Therapeutic results in small-cell bronchial carcinoma after ACO II chemotherapy and adjuvant radiation].[ACO II化疗联合辅助放疗后小细胞支气管癌的治疗结果]
Strahlenther Onkol. 1987 Oct;163(10):637-42.
3
[Small cell lung carcinoma: role of thoracic irradiation and its timing in relation to chemotherapy].小细胞肺癌:胸部放疗的作用及其与化疗相关的时机选择
Bull Cancer. 1994 Feb;81(2):119-28.
4
Combination chemotherapy and radiation therapy for small cell carcinoma.小细胞癌的联合化疗与放射治疗
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[Combination radiochemotherapy in the limited-disease stage of small-cell bronchial carcinoma. Results following high-dosage radiotherapy].[小细胞支气管癌局限期的联合放化疗。高剂量放疗后的结果]
Strahlenther Onkol. 1987 May;163(5):292-6.
6
[Polychemotherapy in inoperable bronchial carcinoma].
Strahlentherapie. 1984 Feb;160(2):71-6.
7
Chemotherapy for small cell bronchogenic carcinoma: CCNU and doxorubicin compared to CCNU, doxorubicin, vincristine, and procarbazine.小细胞支气管癌的化疗:洛莫司汀与阿霉素联合用药与洛莫司汀、阿霉素、长春新碱及丙卡巴肼联合用药的比较
Cancer Treat Rep. 1980 Aug-Sep;64(8-9):997-1000.
8
Three-drug chemotherapy combined with radiation therapy in small cell carcinoma of the lung.
Eur J Respir Dis. 1983 Feb;64(2):113-20.
9
Methotrexate in the chemotherapy of lung cancer.甲氨蝶呤在肺癌化疗中的应用。
Cancer Treat Rep. 1981;65 Suppl 1:161-3.
10
Treatment of modified Stage II (T1 N1 M0, T2 N1 M0) non-small cell bronchogenic carcinoma. A combined modality approach.改良II期(T1 N1 M0、T2 N1 M0)非小细胞支气管源性癌的治疗。一种综合治疗方法。
J Thorac Cardiovasc Surg. 1983 Aug;86(2):180-5.