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[小细胞支气管癌的联合治疗]

[Combination treatment of small cell bronchial carcinoma].

作者信息

Voss A C, Steinke B, Ostendorf P, Teller P, Gnann H

出版信息

Strahlentherapie. 1983 Jan;159(1):18-21.

PMID:6301108
Abstract

35 cases with micro-cellular bronchial carcinoma are described. The patients are treated with a combination of a modified ACO scheme and fractionated irradiations with 50 to 60 Gy to the primary tumor and 30 Gy to the encephalic skull. Among 14 patients with local disease, ten had a complete remission and three a partial remission. Among 21 patients with advanced disease, six had a complete remission and eight a partial remission. The side effects were not important, and they were not reinforced by the higher dose of the primary irradiation. The local recurrence rate was decreased, but the average survival times were not prolonged, because these are still dependent upon the hematogenic formation of metastases.

摘要

本文描述了35例微细胞支气管癌患者。患者接受改良ACO方案联合分次放疗,原发肿瘤剂量为50至60 Gy,脑颅骨剂量为30 Gy。在14例局部病变患者中,10例完全缓解,3例部分缓解。在21例晚期病变患者中,6例完全缓解,8例部分缓解。副作用并不严重,且较高剂量的原发照射并未加重副作用。局部复发率降低,但平均生存时间并未延长,因为这仍取决于转移灶的血行形成。

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