White T R, Thompson R C, Penhale W J
Z Parasitenkd. 1983;69(1):91-104. doi: 10.1007/BF00934013.
Previous work has shown that C57BL/6 mice had the lowest initial susceptibility to Mesocestoides corti of six strains of mice examined. Parasite burdens in this strain and in CBA/H mice, a strain showing a higher initial susceptibility to M. corti, were compared following selective immunosuppressive treatments. Irradiation, splenectomy and the administration of cyclophosphamide and methyl prednisolone all resulted in higher parasite burdens in C57BL/6 mice. In contrast these treatments had a minimal effect on parasite burdens in CBA/H mice. In the light of these results the role of antibody in controlling parasite proliferation is discussed.
先前的研究表明，在检测的六个品系小鼠中，C57BL/6小鼠对中殖孔绦虫的初始易感性最低。在进行选择性免疫抑制治疗后，比较了该品系小鼠和CBA/H小鼠（一种对中殖孔绦虫初始易感性较高的品系）体内的寄生虫负荷。照射、脾切除以及给予环磷酰胺和甲基泼尼松龙均导致C57BL/6小鼠体内的寄生虫负荷增加。相比之下，这些治疗对CBA/H小鼠体内的寄生虫负荷影响极小。根据这些结果，讨论了抗体在控制寄生虫增殖中的作用。
