Rich P R
Biochim Biophys Acta. 1983 Feb 17;722(2):271-80. doi: 10.1016/0005-2728(83)90073-7.
(1) A kinetic analysis of electron donation into and through the cytochrome b-c1 complex isolated from bovine heart mitochondria has been undertaken, using trimethoquinol as the donor. (2) Rate constants of two routes of redox equilibration with quinols have been defined by kinetic measurements and with the use of the inhibitors antimycin A and myxothiazol. (3) A model of electron transfer based upon the original Q-cycle formulation is presented to explain these and related results.
(1)利用三甲氧喹啉作为供体,对从牛心线粒体分离出的细胞色素b-c1复合物的电子供入和通过该复合物的过程进行了动力学分析。(2)通过动力学测量以及使用抑制剂抗霉素A和粘噻唑,确定了与喹醇进行氧化还原平衡的两条途径的速率常数。(3)提出了一个基于原始Q循环公式的电子转移模型来解释这些结果及相关结果。