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β-内啡肽在大鼠垂体门脉血管中含量很高。

beta-Endorphin is present in high concentration in the hypophysial portal vessels of rats.

作者信息

Lissitzky J C, Giraud P, Conte-Devolx B, Gillioz P, Boudouresque F, Eskay R L, Oliver C

出版信息

Neurosci Lett. 1980 Sep;19(2):191-5. doi: 10.1016/0304-3940(80)90193-7.

DOI:10.1016/0304-3940(80)90193-7
PMID:6302596
Abstract

beta-Endorphin-like immunoreactivity (beta-ELI) was measured in hypophysial portal and arterial blood of intact, adrenalectomized and hypophysectomized rats. beta-ELI levels were 61 times higher in the long portal vessels than in the general circulation. Circulating, and especially portal, levels of beta-ELI were significantly increased after adrenalectomy. After removal of the pituitary gland, the mean level of beta-ELI in portal blood was significantly lower than in intact rats. beta-ELI in portal blood displayed the same chromatographic properties as synthetic beta-endorphin.

摘要

在完整、肾上腺切除和垂体切除大鼠的垂体门脉血和动脉血中检测了β-内啡肽样免疫反应性(β-ELI)。长门静脉血管中的β-ELI水平比体循环中的高61倍。肾上腺切除术后,β-ELI的循环水平,尤其是门脉水平显著升高。切除垂体后,门脉血中β-ELI的平均水平显著低于完整大鼠。门脉血中的β-ELI具有与合成β-内啡肽相同的色谱特性。

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2
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