Chamberlain G V, Lewis P J, De Swiet M, Bulpitt C J
Br Med J. 1978 Mar 11;1(6113):626-9. doi: 10.1136/bmj.1.6113.626.
One thousand and ninety-three obstetricians answered a questionnaire on the management of pregnant women with pre-existing hypertension and pre-eclampsia. They reported that they frequently used antihypertensive drugs (most often methyldopa and diuretics) in severe essential hypertension but tended to give sedatives in mild cases. Renal impairment was considered more important that raised blood pressure as an indication for terminating pregnancy; but even without a raised blood urea concentration over a quarter of respondents (especially the more senior obstetricians) would have considered it. The more junior obstetricians were more likely to admit the least severely affected patients to hospital. Pre-eclampsia was usually treated with bed rest and sedatives (most frequently diazepam); but the choice of drug varied with the seniority of the respondents, the more senior obstetricians tending to confine themselves to the more familial drugs. There was considerable unanimity in the replies, even though most of the treatments and practices have not been validated by controlled trials, and two-thirds of the obstetricians gave the same answers to most of the questions.
1093名产科医生回答了一份关于患有慢性高血压和先兆子痫孕妇管理的调查问卷。他们报告称，在重度原发性高血压中，他们经常使用降压药（最常用的是甲基多巴和利尿剂），而在轻度病例中则倾向于使用镇静剂。肾功能损害被认为比血压升高更重要，是终止妊娠的指征；但即使血尿素浓度没有升高，超过四分之一的受访者（尤其是资深产科医生）也会考虑终止妊娠。资历较浅的产科医生更有可能收治病情最轻的患者。先兆子痫通常采用卧床休息和镇静剂（最常用地西泮）治疗；但药物的选择因受访者的资历而异，资历较深的产科医生倾向于只使用更常用的药物。尽管大多数治疗方法和做法尚未经过对照试验验证，但回复中仍有相当一致的意见，三分之二的产科医生对大多数问题给出了相同的答案。
