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每日服用1300毫克阿司匹林不会导致粪便潜血试验呈阳性。

1,300 mg of aspirin daily does not cause positive fecal hemoccult tests.

作者信息

Norfleet R G

出版信息

J Clin Gastroenterol. 1983 Apr;5(2):123-5. doi: 10.1097/00004836-198304000-00006.

DOI:10.1097/00004836-198304000-00006
PMID:6304182
Abstract

Americans 50 years of age and older are advised to test their stools for occult blood to detect colorectal neoplasms. Many will be taking 1,300 mg of aspirin daily because of cerebrovascular disease or smaller amounts for cardiovascular disease. To determine if 1,300 mg of aspirin causes positive hemoccult II tests, 27 healthy volunteers ate a red meat-free, high-fiber diet. Their stools were negative for occult blood during a 3-day control period and remained negative while they took 1,300 mg aspirin daily for an additional 7 days. This indicates that 1,300 mg aspirin daily for 1 week does not cause positive hemoccult II testing. Those taking this dose of aspirin probably need not interrupt therapy to perform hemoccult II testing.

摘要

建议50岁及以上的美国人检测大便潜血以发现结直肠肿瘤。许多人因脑血管疾病每天服用1300毫克阿司匹林,或因心血管疾病服用较少量的阿司匹林。为了确定1300毫克阿司匹林是否会导致隐血试验II呈阳性,27名健康志愿者食用不含红肉的高纤维饮食。在为期3天的对照期内,他们的大便潜血呈阴性,在接下来的7天每天服用1300毫克阿司匹林期间,大便潜血仍为阴性。这表明连续1周每天服用1300毫克阿司匹林不会导致隐血试验II呈阳性。服用此剂量阿司匹林的人可能无需中断治疗来进行隐血试验II检测。

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1,300 mg of aspirin daily does not cause positive fecal hemoccult tests.每日服用1300毫克阿司匹林不会导致粪便潜血试验呈阳性。
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Are medication restrictions before FOBT necessary?: practical advice based on a systematic review of the literature.行 FOBT 检查前是否需要限制用药?:基于文献系统评价的实用建议。
Can Fam Physician. 2012 Sep;58(9):939-48.
2
Fecal occult blood test in patients on low-dose aspirin, warfarin, clopidogrel, or non-steroidal anti-inflammatory drugs.低剂量阿司匹林、华法林、氯吡格雷或非甾体抗炎药患者的粪便隐血试验。
Dig Dis Sci. 2010 Jun;55(6):1637-42. doi: 10.1007/s10620-010-1150-4. Epub 2010 Mar 3.
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Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme.
阿司匹林和非甾体抗炎药对结肠直肠腺瘤的影响:参与诺丁汉粪便潜血筛查项目受试者的病例对照研究
BMJ. 1993 Jul 31;307(6899):285-9. doi: 10.1136/bmj.307.6899.285.
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The pros and cons of fecal occult blood testing for colorectal neoplasms.粪便潜血检测用于结直肠肿瘤的利弊
Cancer Metastasis Rev. 1987;6(3):397-411. doi: 10.1007/BF00144272.
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Influence of non-steroidal anti-inflammatory drugs in faecal occult blood tests.非甾体抗炎药对粪便潜血试验的影响。
Br Med J (Clin Res Ed). 1987 Aug 15;295(6595):446. doi: 10.1136/bmj.295.6595.446-a.