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Reserpine and breast cancer.

作者信息

Kodlin D, McCarthy N

出版信息

Cancer. 1978 Feb;41(2):761-8. doi: 10.1002/1097-0142(197802)41:2<761::aid-cncr2820410250>3.0.co;2-2.

DOI:10.1002/1097-0142(197802)41:2<761::aid-cncr2820410250>3.0.co;2-2
PMID:630550
Abstract

After a series of studies on the linkage of reserpine with breast cancer, both evidence and interpretation appeared to be in conflict. Our case-control survey of long-term, comprehensive records from the Kaiser Foundation Medical Care Program, on 108 hypertensive breast cancer cases and 324 hypertensive controls, matched by year of birth and by race, produces a significant positive association between reserpine use and breast cancer. However, the association vanishes upon further matching with respect to the year of the first hypertension diagnosis and the subsequent length of follow-up. We thus fail to support suspicions of causality.

摘要

相似文献

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Reserpine and breast cancer.
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Reserpine use in relation to breast cancer.利血平与乳腺癌的关系。
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引用本文的文献

1
Carcinogenicity of antihypertensive therapy.抗高血压治疗的致癌性。
Curr Hypertens Rep. 2002 Jun;4(3):195-201. doi: 10.1007/s11906-002-0007-4.
2
Prolactin secretion during reserpine and syrosingopine treatment.利血平和蛇根亭宁治疗期间的催乳素分泌。
Eur J Clin Pharmacol. 1981;20(5):347-9. doi: 10.1007/BF00615404.
3
Reserpine: a relic from the past or a neglected drug of the present for achieving cost containment in treating hypertension?利血平：是过去的遗留物还是当下为控制高血压治疗成本而被忽视的药物？
J Gen Intern Med. 1991 Nov-Dec;6(6):561-72. doi: 10.1007/BF02598229.