Spiesser R, Saint-André J P, Houssin A, Simard C, Riberi P
Sem Hop. 1983 Apr 14;59(15):1171-7.
The authors report their experience with glomerular lesions after renal transplantation, but exclude recurrent glomerulonephritis. Fourteen cases (3 membranous glomerulopathies and eleven allograft glomerulopathies) are discussed in relation to 98 recipients of 105 renal allografts. Two patients with membranous glomerulopathy had HBs antigen in their serum. A poor graft prognosis is observed in 2 of 3 patients. Among eleven recipients who presented with allograft glomerulopathy, two groups are clearly defined with very different graft prognosis. The severity of the vascular lesions was the sole difference between these two groups. The possible physiopathologic mechanisms of allograft glomerulopathy are discussed. It is worth noting that the role of vesico-ureteric reflux is not a prominent feature of this study.
作者报告了他们在肾移植后肾小球病变方面的经验,但排除了复发性肾小球肾炎。针对105例肾移植的98名受者,讨论了14例病例(3例膜性肾小球病和11例移植肾肾小球病)。2例膜性肾小球病患者血清中有乙肝表面抗原。3例患者中有2例观察到移植肾预后不良。在出现移植肾肾小球病的11名受者中,明确分为两组,移植肾预后差异很大。这两组之间唯一的区别是血管病变的严重程度。讨论了移植肾肾小球病可能的病理生理机制。值得注意的是,膀胱输尿管反流的作用在本研究中并非突出特征。