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[牛传染性鼻气管炎-传染性脓疱性外阴阴道炎皮肤过敏试验特异性的评估]

[Evaluation of the specificity of skin allergy tests in cattle with IBR-IPV].

作者信息

Ivanov I E, Arsov R, Sizov I, Terziev S

出版信息

Vet Med Nauki. 1983;20(1):30-5.

PMID:6306906
Abstract

An allergic and serologic investigation was carried out by the skin allergic test (SAT) and the virus neutralization test (VNT) to demonstrate the presence of infectious bovine rhinotracheitis -- infectious pustular vulvovaginitis (IBR-IPV) in cattle divided into three groups according to age, treated with the live attenuated vaccine MK25 against Aujeszky's disease. It was found that this vaccine induced the production of specific antibodies against the virus of IBR-IPV, which could be demonstrated through VNT (beta-variant) in low titers (2-2.5 log10), while through VNT (alfa-variant) no specific antibodies could be found. On the other hand, the virus of Aujeszky's disease did not usually lead or on very rare occasions (massive virus doses and continuous antigenic challenge) led to allergization of the body of cattle for IBR-IPV as well as to a positive SAT. Out of a total of 30 investigated calves only one proved positive by SAT, and 2 others were suspected of being carriers of infection. The problem is discussed of the specificity of SAT and its diagnostic value in IBR-IPV under some epizootiologic circumstances.

摘要

通过皮肤过敏试验(SAT)和病毒中和试验(VNT)对牛进行了过敏和血清学调查,以证明在根据年龄分为三组的牛中存在传染性牛鼻气管炎-传染性脓疱性外阴阴道炎(IBR-IPV),这些牛用抗奥耶斯基氏病的减毒活疫苗MK25进行了处理。结果发现,该疫苗诱导产生了针对IBR-IPV病毒的特异性抗体,这些抗体可通过VNT(β变体)以低滴度(2-2.5 log10)显示出来,而通过VNT(α变体)则未发现特异性抗体。另一方面,奥耶斯基氏病病毒通常不会导致或在极少数情况下(大量病毒剂量和持续抗原攻击)导致牛体对IBR-IPV过敏以及SAT呈阳性。在总共30头接受调查的小牛中,只有一头SAT呈阳性,另外2头被怀疑是感染携带者。讨论了在某些流行病学情况下SAT的特异性及其在IBR-IPV中的诊断价值问题。

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