Neuwirth O, Dikstein S
Curr Eye Res. 1982;2(8):565-7. doi: 10.3109/02713688209069182.
Perfusing preswollen deepithelialized rabbit cornea in vitro on its endothelial side with balanced salt solution containing physiological glucose concentration and 10(-6)M adenosine, we can obtain "temperature reversal" from 500-520 microns to less than 400 microns, during 7 hours. Low concentrations of adenosine improve the fluid pump supposedly by inhibiting adenylate cyclase, since c-AMP inhibits the pump.
在体外对预先肿胀且上皮已去除的兔角膜的内皮面灌注含有生理葡萄糖浓度和10⁻⁶M腺苷的平衡盐溶液,在7小时内,我们可以观察到角膜厚度从500 - 520微米出现“温度逆转”,降至400微米以下。低浓度的腺苷可能通过抑制腺苷酸环化酶来改善液体泵功能,因为环磷酸腺苷(c - AMP)会抑制该泵。