Weed J C, Lozier C, Daniel S J
Obstet Gynecol. 1983 Sep;62(3 Suppl):83s-87s.
Two young patients with multifocal, invasive, verrucoid carcinomas of the lower genital tract are described. Viral particles consistent with human papilloma virus were demonstrated by transmission electron microscopy in areas of koilocytotic malignant and nonmalignant epithelium, and both patients had evidence of impaired immune function. The role of human papilloma virus in genital neoplasia is discussed.
本文描述了两名患有下生殖道多灶性、浸润性疣状癌的年轻患者。通过透射电子显微镜在挖空细胞性恶性和非恶性上皮区域发现了与人乳头瘤病毒一致的病毒颗粒，且两名患者均有免疫功能受损的证据。本文还讨论了人乳头瘤病毒在生殖器肿瘤形成中的作用。
