Rouget J P, Goudemand J, Bouqueau F, Caron C, Jaillard J
Sem Hop. 1983 Jun 2;59(22):1661-4.
Repeated thrombophlebitis with pulmonary embolism in a 28-year-old female led to the discovery of a complex malformation of the inferior vena cava which required the insertion of a clip. Three years later, recurrence of phlebitis with appearance of bipolar aphthae, arthritis and a meningeal syndrome led to the diagnosis of Behçet disease. Despite various medications for this disorder and heparin or oral anticoagulant therapy, the thromboembolic disease remained active, accompany with new exacerbations of Behçet disease. Diminished plasma fibrinolytic activity was demonstrated, probably resulting from venous endothelial vascularitis, which aggravates the consequences of the preexisting vascular malformation.
一名28岁女性反复发生血栓性静脉炎并伴有肺栓塞，这导致发现了下腔静脉的复杂畸形，需要置入夹子。三年后，静脉炎复发，并出现双相口疮、关节炎和脑膜综合征，从而诊断为白塞病。尽管针对该疾病使用了各种药物以及肝素或口服抗凝治疗，但血栓栓塞性疾病仍然活跃，并伴有白塞病的新发作。血浆纤维蛋白溶解活性降低，这可能是由静脉内皮血管炎导致的，而这种血管炎会加重先前存在的血管畸形的后果。
