Heltberg O, Bruun B
Acta Pathol Microbiol Immunol Scand B. 1983 Jun;91(3):157-61. doi: 10.1111/j.1699-0463.1983.tb00026.x.
47 staphylococcal reference strains representing 13 species were tested for polymyxin sensitivity using tablet and disc diffusion methods. Corresponding MIC and IC50 values were determined with a plate dilution assay. Coagulase-positive strains were found to be more resistant towards polymyxin, and could thereby be separated from coagulase-negative strains. Furthermore, 100 recently isolated staphylococci from clinical specimens were tested, and again the coagulase-positive strains could be identified by their smaller tablet inhibition zones. We conclude that the polymyxin test is an aid in the fast differentiation of staphylococci in laboratories performing primary sensitivity tests.
使用纸片法和纸片扩散法对代表13个种的47株葡萄球菌参考菌株进行了多粘菌素敏感性测试。通过平板稀释法测定了相应的MIC和IC50值。发现凝固酶阳性菌株对多粘菌素的耐药性更强，因此可以与凝固酶阴性菌株区分开来。此外，对最近从临床标本中分离出的100株葡萄球菌进行了测试，凝固酶阳性菌株同样可以通过其较小的纸片抑菌圈来识别。我们得出结论，在进行初步敏感性测试的实验室中，多粘菌素测试有助于快速鉴别葡萄球菌。
