Schachter J
Am J Med. 1983 Jul 28;75(1B):93-7. doi: 10.1016/0002-9343(83)90078-5.
The case of specimen collection has led to the suggestion that urine might be a useful specimen for the isolation of sexually transmitted disease agents. It would only be an appropriate specimen for agents that infect the urethra, such as Neisseria gonorrhoeae or Chlamydia trachomatis. Comparative tests have shown that culture of urine for chlamydiae (from men with urethritis) or for gonococci from women is an insensitive procedure. Gonococci can be isolated from urine from men at rates essentially equivalent to culture of urethral swabs. If specimens can be processed promptly (to avoid bactericidal effects of urine), culture of urine can likely be useful for screening asymptomatic men for gonococcal infection.
标本采集的情况引发了这样一种观点，即尿液可能是分离性传播疾病病原体的有用标本。对于感染尿道的病原体，如淋病奈瑟菌或沙眼衣原体，尿液才是合适的标本。对比试验表明，对衣原体（来自患有尿道炎的男性）或女性淋病奈瑟菌进行尿液培养是一种不敏感的方法。从男性尿液中分离淋病奈瑟菌的成功率与尿道拭子培养基本相当。如果标本能及时处理（以避免尿液的杀菌作用），尿液培养可能有助于筛查无症状男性的淋球菌感染。
