De Troyer A, Naeije R, Yernault J C, Englert M
Chest. 1978 Mar;73(3):360-3. doi: 10.1378/chest.73.3.360.
Arterial blood gas levels, lung volumes, and diffusing properties for carbon monoxide were measured in 22 patients with uncomplicated acute pancreatitis who had no clinical or radiographic evidence of pulmonary involvement. Mild arterial hypoxemia (less than 75 mm Hg) was present in four patients. The mean values of inspiratory lung volumes were clearly reduced, and the diffusing properties were sharply altered; the mean value for the diffusing capacity of carbon monoxide per unit of lung volume (Krogh's constant [KCO]) was 78 percent of predicted. Four patients with a low KCO in the first four days after an acute episode had normal values when reevaluated one week later. These findings suggest the occurrence, even in mild acute pancreatitis, of transient pulmonary injury mainly localized at the level of the capillaries, leading to decreased gas transfer.
对22例无肺部受累临床或影像学证据的单纯性急性胰腺炎患者进行了动脉血气水平、肺容积和一氧化碳弥散特性的测量。4例患者存在轻度动脉低氧血症（低于75mmHg）。吸气肺容积的平均值明显降低，弥散特性急剧改变；每单位肺容积一氧化碳弥散能力（克罗格常数[KCO]）的平均值为预测值的78%。4例急性发作后头4天KCO较低的患者在1周后重新评估时KCO值正常。这些发现表明，即使在轻度急性胰腺炎中，也会发生主要局限于毛细血管水平的短暂性肺损伤，导致气体交换减少。
