山羊的肠毒血症：用两种不同的菌苗-类毒素疫苗接种后的体液反应和局部组织反应
Enterotoxemia in the goat: the humoral response and local tissue reaction following vaccination with two different bacterin-toxoids.
作者信息
Blackwell T E, Butler D G, Bell J A
出版信息
Can J Comp Med. 1983 Apr;47(2):127-32.
Abstract
A vaccination trial involving 72 goats was designed to compare the epsilon antitoxin titres and local reactions at the injection sites, of two commercial enterotoxemia vaccines. Three dosage regimens were used for each vaccine (12 goats per group). Although no significant differences were noted in humoral immune response between the two vaccines (P = 0.05), one vaccine regime resulted in low titres (P = 0.05) on two occasions. Local tissue reactions at injection sites persisted for six months in 53% of the goats regardless of vaccine used or dosage administered. No immunological basis for the reported differences in vaccine efficacy between sheep and goats was observed in this trial.
摘要
一项涉及72只山羊的疫苗接种试验旨在比较两种商业产气荚膜梭菌D型和E型毒素血症疫苗的ε抗毒素滴度以及注射部位的局部反应。每种疫苗使用了三种剂量方案（每组12只山羊）。尽管两种疫苗之间的体液免疫反应没有显著差异（P = 0.05），但有一种疫苗方案在两次试验中产生了低滴度（P = 0.05）。无论使用何种疫苗或给予何种剂量，53%的山羊注射部位的局部组织反应持续了六个月。在该试验中未观察到绵羊和山羊之间报道的疫苗效力差异的免疫学依据。
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本文引用的文献
1
The production of a basic immunity against pulpy kidney disease.针对软肾病的基础免疫力的产生。
Onderstepoort J Vet Res. 1967 Apr;34(1):65-79.
2
The prevention of enterotoxaemia (pulpy kidney disease) by vaccination.通过接种疫苗预防肠毒血症（软肾病）。
Bull Off Int Epizoot. 1967 Nov-Dec;67(11):1539-67.
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