胰岛素基因附近的DNA插入序列与青少年成年起病型糖尿病无关。
DNA insertion sequences near the insulin gene are not associated with maturity-onset diabetes of young people.
作者信息
Owerbach D, Thomsen B, Johansen K, Lamm L U, Nerup J
出版信息
Diabetologia. 1983 Jul;25(1):18-20. doi: 10.1007/BF00251890.
PMID:6309587
Abstract
The association between DNA insertion sequences located near the insulin gene and the dominantly inherited maturity-onset diabetes of young people was studied in a large family. The distribution of the restriction fragments was compatible with Mendelian segregation. However, no linkage was found between the DNA insertion sequences and this form of diabetes.
摘要
在一个大家庭中研究了位于胰岛素基因附近的DNA插入序列与年轻人显性遗传的成年型糖尿病之间的关联。限制性片段的分布符合孟德尔分离定律。然而，未发现DNA插入序列与这种糖尿病形式之间存在连锁关系。
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