抗gD单克隆抗体可抑制1型单纯疱疹病毒诱导的细胞融合。
Anti-gD monoclonal antibodies inhibit cell fusion induced by herpes simplex virus type 1.
作者信息
Noble A G, Lee G T, Sprague R, Parish M L, Spear P G
出版信息
Virology. 1983 Aug;129(1):218-24. doi: 10.1016/0042-6822(83)90409-9.
PMID:6310880
Abstract
Monoclonal antibodies directed against glycoprotein D of herpes simplex virus completely inhibited fusion of Vero cells infected with type 1 virus. In contrast, several monoclonal antibodies directed against other viral glycoproteins, including B, were ineffective or were only minimally inhibitory at the highest concentrations tested.
摘要
针对单纯疱疹病毒糖蛋白D的单克隆抗体完全抑制了感染1型病毒的Vero细胞的融合。相比之下，几种针对包括糖蛋白B在内的其他病毒糖蛋白的单克隆抗体在测试的最高浓度下无效或仅有轻微抑制作用。
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