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Estimation of the single stranded region in the nuclear DNA of mouse tissues during aging with special reference to the brain.

作者信息

Mori N, Goto S

出版信息

Arch Gerontol Geriatr. 1982 Sep;1(2):143-50. doi: 10.1016/0167-4943(82)90014-0.

DOI:10.1016/0167-4943(82)90014-0
PMID:6311122
Abstract

The proportion of single stranded DNA in various tissues of mouse during aging was examined by measuring sensitivity to a single-strand specific nuclease. Brain DNA from mice of more than 15 mth old contained 3% of the single stranded regions while that from younger animals contained 2%. The DNAs from liver, kidney, heart and spleen did not show significant age-associated changes.

摘要

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