Romanus M, Haljamäe H
Eur Surg Res. 1978;10(1):17-23. doi: 10.1159/000127988.
The effects of pressure-induced ischemia on energy metabolism, measured as ATP and glucose content, is studied in hamster cheek pouch. Metabolic deterioration during ischaemia is studied and after 2 h the glucose content was significantly reduced but not the ATP content, which was significantly reduced after 4 h of ischemia. Restoration of glucose levels in the cheek pouch tissue was achieved within 30 min of recirculation after release of pressure. The cellular energy metabolism is unable after 4 h of ischemia to restore ATP levels in the tissue during the 120-min of postischemic observation time. There is a difference in ability to resume normal energy metabolism after 2 and 4 h of pressure-induced ischemia.
在仓鼠颊囊中研究了压力诱导的缺血对以ATP和葡萄糖含量衡量的能量代谢的影响。研究了缺血期间的代谢恶化情况，2小时后葡萄糖含量显著降低，但ATP含量未降低，缺血4小时后ATP含量显著降低。压力解除后再灌注30分钟内，颊囊组织中的葡萄糖水平得以恢复。缺血4小时后，在120分钟的缺血后观察期内，细胞能量代谢无法恢复组织中的ATP水平。压力诱导的缺血2小时和4小时后恢复正常能量代谢的能力存在差异。
