Grabner G, Smolin G, Okumoto M, Stebbing N
Curr Eye Res. 1982;2(11):785-90. doi: 10.3109/02713688209020012.
Highly purified preparations of two recombinant-DNA derived human leukocyte interferon subtypes (LeIF-A and LeIF-D) and a similarly derived fibroblast interferon were compared for efficacy against herpes simplex virus, type 1, infection of the rabbit cornea. LeIF-D appeared to be more effective than LeIF-A especially when compared on the basis of interferon units. The fibroblast interferon showed no significant effects. The greater activity of LeIF-D compared with LeIF-A could be due to greater direct antiviral effects, as observed in rabbit cell cultures.
对两种重组DNA衍生的人白细胞干扰素亚型（LeIF - A和LeIF - D）以及一种同样衍生的成纤维细胞干扰素的高纯度制剂，就其抗1型单纯疱疹病毒感染兔角膜的功效进行了比较。LeIF - D似乎比LeIF - A更有效，尤其是在基于干扰素单位进行比较时。成纤维细胞干扰素未显示出显著效果。与LeIF - A相比，LeIF - D的活性更高可能是由于在兔细胞培养中观察到的更强的直接抗病毒作用。
