Toyosaka A, Okamoto E, Kuwata K, Ueki S, Okasora T
Gan No Rinsho. 1983 Aug;29(10):1243-52.
Forty-four cases with childhood solid malignancy during the period from 1973 to 1982, were analysed. 11 cases underwent second-look operation, including 4 neuroblastomas, 4 hepatoblastomas, 1 malignant teratoma, 1 nephroblastoma, and 1 rhabdomyosarcoma. Two cases of hepatoblastoma in second-look operation are surviving over two years with no evidence of disease, and one case survived 5 years 8 months. For one patient of initially unresectable neuroblastoma, second-look operation was successfully performed by complete resection followed by paraortic-lymphonode dissection. In two cases of Wilms' tumor and malignant teratoma, second-look operations were performed for the purpose of treatment decision after radical operation. In the unresectable tumors or recurrent tumors or metastatic lesions, complete cure can be expected by aggressive surgical approach and combination chemotherapy followed by second-or third-look operation.
对1973年至1982年间的44例儿童实体恶性肿瘤病例进行了分析。11例患者接受了二次探查手术，其中包括4例神经母细胞瘤、4例肝母细胞瘤、1例恶性畸胎瘤、1例肾母细胞瘤和1例横纹肌肉瘤。二次探查手术中的2例肝母细胞瘤患者存活超过两年，无疾病迹象，1例存活了5年8个月。对于1例最初无法切除的神经母细胞瘤患者，通过完全切除并随后进行腹主动脉旁淋巴结清扫成功实施了二次探查手术。在2例肾母细胞瘤和恶性畸胎瘤病例中，二次探查手术是在根治性手术后为了做出治疗决策而进行的。在无法切除的肿瘤、复发性肿瘤或转移性病变中，通过积极的手术方法和联合化疗，随后进行二次或三次探查手术，可以预期实现完全治愈。
