Middleton R S
J Int Med Res. 1978;6(2):121-5. doi: 10.1177/030006057800600209.
The sleep-inducing properties and tolerance of temazepam formulated in solution in soft gelatine capsules were compared with chlormethiazole syrup in two groups of geriatric in-patients. Both compounds appeared to be safe, effective and well-tolerated, but significant differences in favour of temazepam were observed in quality and duration of sleep, ease of awakening and carry-over effects. This formulation of temazepam (Euhypnos) would appear to be an ideal sleep-inducer for geriatric patients.
在两组老年住院患者中,对软胶囊溶液剂型的替马西泮与氯美噻唑糖浆的助眠特性及耐受性进行了比较。两种药物似乎都安全、有效且耐受性良好,但在睡眠质量和持续时间、唤醒难易程度及残留效应方面观察到有利于替马西泮的显著差异。替马西泮(优眠)的这种剂型似乎是老年患者理想的催眠药。