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感染伪狂犬病病毒的猪的血清学反应。

Serological response of pigs infected with Aujeszky's disease virus.

作者信息

Martin S, Wardley R C, Donaldson A I

出版信息

Res Vet Sci. 1983 Sep;35(2):227-33.

PMID:6314461
Abstract

The temporal development of antibody in four groups of pigs infected with different Aujeszky's disease virus isolates was examined. The enzyme-linked immunosorbent assay detected antibody by five to six days after infection and the antibody-dependent cell-mediated cytotoxicity assay detected antibody seven to nine days after infection. Neutralising antibody was first detected nine to 10 days after infection, whereas assays measuring complement mediated antibody lysis did not detect antibody until 10 days after infection. These results are discussed in terms of their importance to the diagnosis of and recovery from Aujeszky's disease.

摘要

对四组感染不同伪狂犬病病毒分离株的猪体内抗体的时间发展情况进行了检测。酶联免疫吸附测定法在感染后五到六天检测到抗体,而抗体依赖性细胞介导的细胞毒性测定法在感染后七到九天检测到抗体。中和抗体在感染后九到十天首次检测到,而测量补体介导的抗体裂解的测定法直到感染后十天才检测到抗体。根据这些结果对伪狂犬病诊断和康复的重要性进行了讨论。

相似文献

1
Serological response of pigs infected with Aujeszky's disease virus.感染伪狂犬病病毒的猪的血清学反应。
Res Vet Sci. 1983 Sep;35(2):227-33.
2
Local humoral and cellular responses in Aujeszky's disease virus infection in pigs.猪伪狂犬病病毒感染中的局部体液和细胞反应。
Res Vet Sci. 1987 Mar;42(2):170-4.
3
[Cell-mediated cytotoxicity and lymphocyte stimulation in Aujeszky's disease. I. In experimentally infected swine].
Zentralbl Veterinarmed B. 1985 Feb;32(2):101-15.
4
A novel concept for the control of Aujeszky's disease: experiences in two vaccinated pig herds.一种控制奥耶斯基氏病的新观念:两个接种疫苗猪群的经验
Vet Rec. 1990 Feb 17;126(7):159-63.
5
Four-layer enzyme immunoassay (EIA) detection of differences in IgG, IgM and IgA antibody response to Aujeszky's disease virus in infected and vaccinated pigs.四层酶免疫测定法(EIA)检测感染和接种疫苗猪对伪狂犬病病毒的IgG、IgM和IgA抗体反应差异。
Vet Microbiol. 1987 Feb;13(2):121-33. doi: 10.1016/0378-1135(87)90037-x.
6
[Cell-mediated cytotoxicity and lymphocyte stimulation in Aujeszky's disease. II. Following vaccination of swine and subsequent infection].
Zentralbl Veterinarmed B. 1985 Mar;32(3):181-96.
7
Studies on immunity to Aujeszky's disease (pseudorabies) virus infection in pigs.
Dev Biol Stand. 1975;28:563-70.
8
[Serological investigations for detection of neutralising antibodies against the virus of Aujeszky's disease in pedigree breeding - and piglet producing farms in the district of the Animal Health Office in the Chamber of Agriculture Weser-Ems (author's transl)].[在韦瑟尔-埃姆斯农业商会动物卫生局辖区内的谱系繁育场和仔猪生产场进行的检测抗奥耶斯基氏病病毒中和抗体的血清学调查(作者译)]
Dtsch Tierarztl Wochenschr. 1980 Apr 5;87(4):125-7.
9
Enzyme-linked immunosorbent assay for detecting antibodies to Aujeszky's disease virus in pigs.用于检测猪伪狂犬病病毒抗体的酶联免疫吸附测定法。
Vet Rec. 1981 Dec 12;109(24):534-7.
10
[Direct solid-phase radioimmunoassay for the detection of Aujeszky's disease antibodies (author's transl)].
Zentralbl Bakteriol A. 1980 Jun;247(1):1-7.

引用本文的文献

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Vaccine-induced, pseudorabies virus-specific, extrathymic CD4+CD8+ memory T-helper cells in swine.猪体内由疫苗诱导产生的、针对伪狂犬病病毒的胸腺外CD4+CD8+记忆性辅助性T细胞
J Virol. 1998 Jun;72(6):4866-73. doi: 10.1128/JVI.72.6.4866-4873.1998.
2
Characterization of the pseudorabies virus-specific immunoglobulin M response and evaluation of its diagnostic use in pigs with preexisting immunity to the virus.伪狂犬病病毒特异性免疫球蛋白M反应的特征及其在对该病毒具有预先免疫力的猪中的诊断用途评估。
J Clin Microbiol. 1993 Sep;31(9):2309-14. doi: 10.1128/jcm.31.9.2309-2314.1993.
3
Development and evaluation of an indirect enzyme immunoassay for detection of porcine antibodies to pseudorabies virus.
用于检测猪伪狂犬病病毒抗体的间接酶免疫测定法的建立与评估
Can J Vet Res. 1986 Jul;50(3):422-6.
4
Dot-enzyme immunoassay for visual detection of antibodies to pseudorabies virus in swine serum.
J Clin Microbiol. 1986 Mar;23(3):563-7. doi: 10.1128/jcm.23.3.563-567.1986.
5
Pseudorabies virus glycoprotein gIII is a major target antigen for murine and swine virus-specific cytotoxic T lymphocytes.伪狂犬病病毒糖蛋白gIII是小鼠和猪病毒特异性细胞毒性T淋巴细胞的主要靶抗原。
J Virol. 1990 Feb;64(2):802-12. doi: 10.1128/JVI.64.2.802-812.1990.
6
Pseudorabies virus-induced suppression of major histocompatibility complex class I antigen expression.伪狂犬病病毒诱导的主要组织相容性复合体I类抗原表达抑制
J Virol. 1991 Jun;65(6):3365-8. doi: 10.1128/JVI.65.6.3365-3368.1991.
7
Comparative evaluation of an enzyme-linked immunosorbent assay (ELISA) to detect antibodies directed against glycoprotein I of pseudorabies virus and a conventional ELISA and neutralization tests.用于检测抗伪狂犬病病毒糖蛋白I抗体的酶联免疫吸附测定(ELISA)与传统ELISA及中和试验的比较评估
J Clin Microbiol. 1991 Jan;29(1):5-9. doi: 10.1128/jcm.29.1.5-9.1991.
8
Characterization of pseudorabies virus antibody responses in young swine after infection and vaccination by using an immunoglobulin M antibody capture enzyme-linked immunosorbent assay.使用免疫球蛋白M抗体捕获酶联免疫吸附测定法对幼猪感染和接种疫苗后伪狂犬病病毒抗体反应的特征进行研究。
J Clin Microbiol. 1992 Feb;30(2):346-50. doi: 10.1128/jcm.30.2.346-350.1992.