Davies R, Griffiths D M, Preece A W
Environ Health Perspect. 1983 Sep;51:245-8. doi: 10.1289/ehp.8351245.
The cytotoxicity of various ball-milled UICC amosite samples toward mouse peritoneal macrophages in vitro was examined. On increased ball milling, the cytotoxicity of the amosite samples fell. This decreased biological activity seemed to correlate best with number of fibers longer than 4 micron/micrograms dust, rather than total number of fibers or the electrophoretic mobility of the amosite samples.
检测了各种球磨后的国际抗癌联盟(UICC)铁石棉样品在体外对小鼠腹腔巨噬细胞的细胞毒性。随着球磨程度增加,铁石棉样品的细胞毒性降低。这种生物活性的降低似乎与长度超过4微米/微克粉尘的纤维数量最相关,而非铁石棉样品的纤维总数或电泳迁移率。