Garcia Muñoz M, Garcia Domenech R, Galvez Alvarez J, Moreno Frigols J
Int J Appl Radiat Isot. 1983 Nov;34(11):1505-8. doi: 10.1016/0020-708x(83)90284-3.
A kinetic study was made of the ligand exchange reaction between [99mTc]EDTA and DMSA. The results of this study indicate that this exchange reaction is closely related to temperature and pH. Kinetic and thermodynamic parameters demonstrate that both complexes--[99MTc]EDTA and [99mTc]DMSA--have a similar stability. Furthermore, the existence of an acid-basic catalysis for the global exchange reaction was established, and the catalytic parameters were calculated. These data were obtained by radiochromatography and visible spectrophotometry.
对[99mTc]乙二胺四乙酸（EDTA）与二巯基丁二酸（DMSA）之间的配体交换反应进行了动力学研究。该研究结果表明，这种交换反应与温度和pH密切相关。动力学和热力学参数表明，两种配合物——[99mTc]EDTA和[99mTc]DMSA——具有相似的稳定性。此外，确定了整体交换反应存在酸碱催化作用，并计算了催化参数。这些数据通过放射性色谱法和可见分光光度法获得。
