Morgan M Y, Jakobovits A W, Gore M B, Wills M R, Sherlock S
Gut. 1978 Mar;19(3):170-4. doi: 10.1136/gut.19.3.170.
Serum immunoreactive prolactin was measured in 150 patients with liver disease of varying aetiology and severity and in 45 control subjects. The upper limit of the reference range for serum prolactin was 331 mU/l. Eighteen patients with liver disease (12%) had unexplained hyperprolactinaemia. No relationship existed between the prolactin value and the sex of the patient, the aetiology of the liver disease, the severity of the liver disease, or the presence of gynaecomastia. The cause of the hyperprolactinaemia in patients with liver disease and its clinical implications need further investigation.
对150例病因和严重程度各异的肝病患者以及45名对照者测定了血清免疫反应性催乳素。血清催乳素参考范围的上限为331 mU/l。18例肝病患者(12%)存在不明原因的高催乳素血症。催乳素值与患者性别、肝病病因、肝病严重程度或男性乳房发育症的存在均无关联。肝病患者高催乳素血症的原因及其临床意义有待进一步研究。