Stipon J P, Le Bihan Y, de Rotalier P
Sem Hop. 1983 Oct 27;59(39):2735-8.
The authors report the results obtained with a new analgesic, UP 341.01, which is a bioprecursor of paracetamol. Two groups of patients with acute pain, due to suppurative acute otitis media before myringotomy, were given an intravenous injection of 1 or 2 g of UP 341.01 respectively. Changes in the severity of pain were assessed over five hours by means of a verbal five point scoring system. During this study, UP 341.01 proved efficient and well tolerated.
作者报告了一种新型镇痛药UP 341.01的研究结果，它是对乙酰氨基酚的生物前体。两组因急性化脓性中耳炎行鼓膜切开术前出现急性疼痛的患者，分别静脉注射1克或2克UP 341.01。采用言语五点评分系统评估五小时内疼痛严重程度的变化。在这项研究中，UP 341.01被证明有效且耐受性良好。
