Knothe H
Wien Klin Wochenschr Suppl. 1983;142:4-7.
From 1979 to 1982, a large number of freshly isolated strains of bacteria were investigated at our institute with regard to their sensitivity to cefotaxime in comparison to other antibiotics. The isolates came from 42 clinics in the Rhine-Main region. The results of the investigations demonstrate that cefotaxime, due to its high stability against beta-lactamases, has advantages over to older cephalosporins, and even cefoperazon and cefoxitin. Despite increased use of cefotaxime, there was no change in the sensitivity of the organisms from 1979 to 1982.
1979年至1982年期间，我院对大量新分离出的细菌菌株进行了研究，比较了它们对头孢噻肟与其他抗生素的敏感性。这些分离菌株来自莱茵-美因地区的42家诊所。研究结果表明，头孢噻肟由于对β-内酰胺酶具有高度稳定性，比旧的头孢菌素甚至头孢哌酮和头孢西丁更具优势。尽管头孢噻肟的使用有所增加，但从1979年到1982年，这些微生物的敏感性并未改变。
