Kelly B W, Morris J F, Harwood B P, Bruya T E
Cancer. 1984 Jan 1;53(1):99-102. doi: 10.1002/1097-0142(19840101)53:1<99::aid-cncr2820530118>3.0.co;2-z.
The technique and predictive value for survival of initial and restaging bone marrow examinations in small cell carcinoma (SCC) of the lung were evaluated by 76 examinations of 72 patients. In 76 examinations, only 2 (2.6%) of the bilateral iliac crest bone marrow examinations revealed tumor cells unilaterally and these two were restaging examinations. If SCC was found in the marrow, bone marrow biopsy was always positive. In no instance was an aspirate positive with a negative bone marrow biopsy. Thus a unilateral bone marrow biopsy is an adequate technique for the initial staging of the bone marrow in SCC of the lung. Survival of patients with or without positive initial bone marrow examinations was not significantly different.
通过对72例患者进行76次检查，评估了肺小细胞癌（SCC）初次及再分期骨髓检查的技术及生存预测价值。在76次检查中，双侧髂嵴骨髓检查仅2次（2.6%）单侧发现肿瘤细胞，且这两次均为再分期检查。若在骨髓中发现SCC，骨髓活检总是阳性。骨髓穿刺抽吸物阳性而骨髓活检阴性的情况从未出现。因此，单侧骨髓活检是肺SCC骨髓初始分期的一种充分技术。初次骨髓检查阳性或阴性的患者生存率无显著差异。
