Hesse J, Ibsen K K, Krabbe S, Uldall P
Scand J Infect Dis. 1983;15(4):335-8. doi: 10.3109/inf.1983.15.issue-4.03.
A seroepidemiologic survey on the prevalence of antibodies to Epstein-Barr virus (EBV) in Denmark was carried out. Sera from 518 children and 178 adults were investigated for IgG antibodies to the viral capsid antigen by an immunofluorescence assay. The proportion of subjects with antibodies increased from 15% at 1 yr to 60-65% in the 4-6 yr age group, was stationary at the age of 7-14, and then increased further progressively with age, to reach about 95% in late adulthood. Among preschool children a significantly higher prevalence rate was demonstrated in the lower socioeconomic stratum, as well as a somewhat higher prevalence rate in children attending day nurseries. The study indicates that infections with EBV have a rather early and widespread occurrence in this country compared with other developed areas.
在丹麦开展了一项关于爱泼斯坦 - 巴尔病毒（EBV）抗体流行率的血清流行病学调查。通过免疫荧光测定法，对518名儿童和178名成人的血清进行了病毒衣壳抗原IgG抗体检测。有抗体的受试者比例从1岁时的15%增加到4 - 6岁年龄组的60 - 65%，在7 - 14岁时保持稳定，然后随着年龄进一步逐渐增加，在成年后期达到约95%。在学龄前儿童中，社会经济地位较低阶层的患病率明显较高，在日托所儿童中的患病率也略高。该研究表明，与其他发达地区相比，EBV感染在该国相当早且广泛地发生。
