Edwards S, Roeder P L
Vet Microbiol. 1983 Nov;8(6):563-9. doi: 10.1016/0378-1135(83)90005-6.
Three calves, latently infected with bovine herpesvirus 1 (BHV 1), were each inoculated intranasally with 9 strains of ruminant pestivirus (BVDV). All three calves developed a biphasic pyrexia and a lymphopenia followed by a neutrophilia. They did not shed BHV 1 in their nasal secretions in the 14 days following BVDV inoculation, and their BHV 1 antibody levels remained static, as did those of 2 control calves not given BVDV. All five calves were subsequently shown to be latently infected with BHV 1 by the production of recrudescent infections following the administration of dexamethasone. BHV 1 was recovered from nasal secretions and there was a marked rise in BHV 1 antibody titres in the second week after dexamethasone administration.
三头潜伏感染牛疱疹病毒1型(BHV 1)的犊牛,每头经鼻接种9株反刍动物瘟病毒(BVDV)。所有三头犊牛均出现双相发热和淋巴细胞减少,随后出现嗜中性粒细胞增多。在接种BVDV后的14天内,它们的鼻分泌物中未排出BHV 1,其BHV 1抗体水平保持稳定,未接种BVDV的2头对照犊牛的抗体水平也是如此。随后,通过给予地塞米松后产生再发感染,证明所有五头犊牛均潜伏感染BHV 1。从鼻分泌物中分离出BHV 1,且在地塞米松给药后的第二周,BHV 1抗体滴度显著升高。