Aronoff S C, Murdell D, O'Brien C A, Klinger J D, Reed M D, Blumer J L
Antimicrob Agents Chemother. 1983 Nov;24(5):663-6. doi: 10.1128/AAC.24.5.663.
Thirty-four patients aged 1 month to 19 years were treated with ceftriaxone for suspected bacterial infections. Bacterial pathogens were isolated from 25 children. The overall bacterial cure rate was 88%, with an overall clinical response rate of 96%. No side effects requiring cessation of therapy were observed. Ceftriaxone proved to be safe and effective in the treatment of serious infections in children.
34名年龄在1个月至19岁之间的患者因疑似细菌感染接受了头孢曲松治疗。从25名儿童中分离出了细菌病原体。总体细菌治愈率为88%,总体临床有效率为96%。未观察到需要停止治疗的副作用。头孢曲松被证明在治疗儿童严重感染方面安全有效。