13种β-内酰胺类抗生素的比较活性
Comparative activities of 13 beta-lactam antibiotics.
作者信息
Muytjens H L, van der Ros-van de Repe J
出版信息
Antimicrob Agents Chemother. 1982 Jun;21(6):925-34. doi: 10.1128/AAC.21.6.925.
Abstract
An agar dilution method was used to measure the minimal inhibitory concentrations of 13 beta-lactam antibiotics against 868 recent human clinical isolates. Most members of the Enterobacteriaceae were susceptible to cefoperazone, ceftazidime, moxalactam, N-formimidoyl thienamycin, ceftriaxone, and ceftizoxime. Cephalothin was the most active antibiotic against Staphylococcus aureus. Most strains of Pseudomonas aeruginosa were inhibited by ceftazidime, N-formimidoyl thienamycin, and cefsulodin. N-Formimidoyl thienamycin was active against all of the species tested.
摘要
采用琼脂稀释法测定了13种β-内酰胺类抗生素对868株近期人类临床分离菌的最低抑菌浓度。肠杆菌科的大多数成员对头孢哌酮、头孢他啶、拉氧头孢、亚胺培南、头孢曲松和头孢唑肟敏感。头孢噻吩是对金黄色葡萄球菌活性最强的抗生素。大多数铜绿假单胞菌菌株被头孢他啶、亚胺培南和头孢磺啶抑制。亚胺培南对所有测试菌种均有活性。
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