Zverkov I V, Dmitriev A D, Veselova S P, Vinogradov V A, Smagin V G
Biull Eksp Biol Med. 1984 Jan;97(1):28-31.
Immunohistochemistry was used to study the changes in the number of G cells in the antral part of the stomach of rats (40 animals) with cystamine-induced duodenal ulcer treated with beta-endorphine. In the stomach of rats with cystamine-induced ulcer the number of G cells was discovered to be significantly increased, which was removed by an opioid peptide. Naloxone did not block the action of beta-endorphine. Thus, beta-endorphine changes the number of G cells, the drug action being not associated with opiate receptors.
采用免疫组织化学方法研究了用β-内啡肽治疗胱胺诱导十二指肠溃疡的大鼠（40只）胃窦部G细胞数量的变化。在胱胺诱导溃疡的大鼠胃中，发现G细胞数量显著增加，而阿片肽可消除这种增加。纳洛酮不能阻断β-内啡肽的作用。因此，β-内啡肽改变G细胞数量，该药物作用与阿片受体无关。
