Isacsohn M, Berson B, Sternberg I, Morag A
Isr J Med Sci. 1983 Nov;19(11):959-62.
The therapeutic effect of human fibroblast interferon (HFIF) was studied in 33 patients. Seven had ophthalmic lesions (three due to adenovirus Type 8, four to herpes simplex virus, and one to herpes zoster) and were treated with HFIF. In the four patients with herpes simplex keratitis, HFIF was given in addition to standard therapy or together with other antiviral agents. Ten other patients, 8 with herpes simplex or herpes zoster skin or mucous membrane lesions, were treated with HFIF. HFIF was incorporated into an ointment as well as into a solution for subconjunctival infections. Although the number of cases was small, our results showed that HFIF was effective in shortening the course of the disease.
对33例患者研究了人成纤维细胞干扰素（HFIF）的治疗效果。7例有眼部病变（3例由8型腺病毒引起，4例由单纯疱疹病毒引起，1例由带状疱疹引起），接受了HFIF治疗。在4例单纯疱疹性角膜炎患者中，除标准治疗外还给予了HFIF，或与其他抗病毒药物联合使用。另外10例患者，8例有单纯疱疹或带状疱疹皮肤或黏膜病变，接受了HFIF治疗。HFIF被制成软膏以及用于结膜下注射的溶液。虽然病例数较少，但我们的结果表明HFIF能有效缩短病程。
