Udvardy A, Schedl P
J Mol Biol. 1984 Feb 5;172(4):385-403. doi: 10.1016/s0022-2836(84)80013-3.
We have examined the chromatin structure of the hsp 70 gene complex at the 87A7 heat shock locus of Drosophila melanogaster. Our results indicate that this locus has a complex chromatin organization. Heat induction causes highly specific alterations in the chromatin throughout the locus. There are major changes within the heat shock gene transcription units, and in both the upstream and downstream flanking spacers.
我们研究了黑腹果蝇87A7热休克位点处hsp 70基因复合体的染色质结构。我们的结果表明,该位点具有复杂的染色质组织。热诱导会导致整个位点的染色质发生高度特异性的改变。热休克基因转录单元内部以及上游和下游侧翼间隔区均有重大变化。