酮康唑治疗后出现的中毒性肝炎。
Toxic hepatitis following ketoconazole treatment.
作者信息
Svedhem A
出版信息
Scand J Infect Dis. 1984;16(1):123-5. doi: 10.3109/00365548409068418.
PMID:6320358
Abstract
Ketoconazole, a new broad-spectrum oral antifungal agent, has proved most useful in the treatment of superficial and systemic fungal infections. Chronic conditions like mucocutaneous candidiasis can be treated with but few side effects. An increasing number of cases have, however, been noted of severe toxic hepatitis, following ketoconazole treatment. A new case (a 61-yr-old woman treated for onychomycosis) is reported here.
摘要
酮康唑是一种新型广谱口服抗真菌药物，已被证明在治疗浅表和全身性真菌感染方面非常有用。像黏膜皮肤念珠菌病这样的慢性病可用其治疗，且副作用很少。然而，越来越多的病例显示，酮康唑治疗后出现了严重的中毒性肝炎。本文报告了一例新病例（一名61岁因甲癣接受治疗的女性）。
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