Neufeld A H, Bartels S P, Liu J H
Surv Ophthalmol. 1983 Dec;28 Suppl:286-92. doi: 10.1016/0039-6257(83)90152-2.
Timolol is now widely used in the treatment of glaucoma but its mechanism of action is unclear. The drug decreases aqueous humor formation by the ciliary processes and is a potent beta-adrenergic antagonist. However, the physiological basis for such a drug to decrease intraocular pressure has not been clearly demonstrated.